| Short Description : | Rabbit polyclonal anti-Phospho-RNA polymerase I-specific transcription initiation factor RRN3-Ser649 (602-651 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RRN3 |
| Gene ID: | 54700 |
| Uniprot ID: | RRN3_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human TIF-IA around the phosphorylation site of Ser649 at the amino acid range 602-651 |
| Immunogen Region: | 602-651 aa |
| Specificity: | Phospho-Rrn3 (S649) Polyclonal Antibody detects endogenous levels of Rrn3 protein only when phosphorylated at S649. |
| Function | Required for efficient transcription initiation by RNA polymerase I (Pol I). Required for the formation of the competent pre-initiation complex (PIC). |
| Protein Name | Rna Polymerase I-Specific Transcription Initiation Factor Rrn3Transcription Initiation Factor IaTif-Ia |
| Database Links | Reactome: R-HSA-73762Reactome: R-HSA-73772 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Rna Polymerase I-Specific Transcription Initiation Factor Rrn3 antibodyAnti-Transcription Initiation Factor Ia antibodyAnti-Tif-Ia antibodyAnti-RRN3 antibodyAnti-TIFIA antibody |
Information sourced from Uniprot.org
