| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phospho-Small ribosomal subunit protein eS6-Ser240 (200-249 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RPS6 |
| Gene ID: | 6194 |
| Uniprot ID: | RS6_HUMAN |
| Immunogen Region: | 200-249 aa |
| Specificity: | Phospho-Ribosomal Protein S6 (S240) Polyclonal Antibody detects endogenous levels of Ribosomal Protein S6 protein only when phosphorylated at S240. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human S6 Ribosomal Protein around the phosphorylation site of Ser240 at the amino acid range 200-249 |
| Function | Component of the 40S small ribosomal subunit. Plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. |
| Protein Name | Small Ribosomal Subunit Protein Es6 40s Ribosomal Protein S6 Phosphoprotein Np33 |
| Database Links | Reactome: R-HSA-156827 Reactome: R-HSA-156902 Reactome: R-HSA-166208 Reactome: R-HSA-1799339 Reactome: R-HSA-192823 Reactome: R-HSA-2408557 Reactome: R-HSA-6790901 Reactome: R-HSA-6791226 Reactome: R-HSA-72649 Reactome: R-HSA-72689 Reactome: R-HSA-72695 Reactome: R-HSA-72702 Reactome: R-HSA-72706 Reactome: R-HSA-72764 Reactome: R-HSA-9010553 Reactome: R-HSA-9629569 Reactome: R-HSA-9633012 Reactome: R-HSA-9725371 Reactome: R-HSA-9735869 Reactome: R-HSA-9754678 Reactome: R-HSA-975956 Reactome: R-HSA-975957 |
| Cellular Localisation | Cytoplasm Nucleus Nucleolus |
| Alternative Antibody Names | Anti-Small Ribosomal Subunit Protein Es6 antibody Anti-40s Ribosomal Protein S6 antibody Anti-Phosphoprotein Np33 antibody Anti-RPS6 antibody Anti-OK antibody Anti-SW-cl.2 antibody |
Information sourced from Uniprot.org