Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Phospho-Prostaglandin E synthase 3-Ser113 (79-128 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PTGES3 |
Gene ID: |
10728 |
Uniprot ID: |
TEBP_HUMAN |
Immunogen Region: |
79-128 aa |
Specificity: |
Phospho-p23 (S113) Polyclonal Antibody detects endogenous levels of p23 protein only when phosphorylated at S113. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human TEBP around the phosphorylation site of Ser113 at the amino acid range 79-128 |
Function | Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway. |
Protein Name | Prostaglandin E Synthase 3Cytosolic Prostaglandin E2 SynthaseCpgesHsp90 Co-ChaperoneProgesterone Receptor Complex P23Telomerase-Binding Protein P23 |
Database Links | Reactome: R-HSA-2162123Reactome: R-HSA-3371497Reactome: R-HSA-3371511Reactome: R-HSA-3371568Reactome: R-HSA-8937144Reactome: R-HSA-8939211Reactome: R-HSA-9018519Reactome: R-HSA-9679191 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Prostaglandin E Synthase 3 antibodyAnti-Cytosolic Prostaglandin E2 Synthase antibodyAnti-Cpges antibodyAnti-Hsp90 Co-Chaperone antibodyAnti-Progesterone Receptor Complex P23 antibodyAnti-Telomerase-Binding Protein P23 antibodyAnti-PTGES3 antibodyAnti-P23 antibodyAnti-TEBP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance