• Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using TEBP (Phospho-Ser113) Antibody. The picture on the right is blocked with the phospho peptide.
  • Western blot analysis of lysates from NIH/3T3 cells treated with EGF 200ng/ml 30', using TEBP (Phospho-Ser113) Antibody. The lane on the right is blocked with the phospho peptide.
  • Western blot analysis of 3T3 cells using Phospho-p23 (S113) Polyclonal Antibody

Anti-Phospho-PTGES3-Ser113 antibody (79-128 aa) (STJ90833)

SKU:
STJ90833

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Prostaglandin E synthase 3-Ser113 (79-128 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PTGES3
Gene ID: 10728
Uniprot ID: TEBP_HUMAN
Immunogen Region: 79-128 aa
Specificity: Phospho-p23 (S113) Polyclonal Antibody detects endogenous levels of p23 protein only when phosphorylated at S113.
Immunogen: The antiserum was produced against synthesized peptide derived from the human TEBP around the phosphorylation site of Ser113 at the amino acid range 79-128
Function Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.
Protein Name Prostaglandin E Synthase 3
Cytosolic Prostaglandin E2 Synthase
Cpges
Hsp90 Co-Chaperone
Progesterone Receptor Complex P23
Telomerase-Binding Protein P23
Database Links Reactome: R-HSA-2162123
Reactome: R-HSA-3371497
Reactome: R-HSA-3371511
Reactome: R-HSA-3371568
Reactome: R-HSA-8937144
Reactome: R-HSA-8939211
Reactome: R-HSA-9018519
Reactome: R-HSA-9679191
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Prostaglandin E Synthase 3 antibody
Anti-Cytosolic Prostaglandin E2 Synthase antibody
Anti-Cpges antibody
Anti-Hsp90 Co-Chaperone antibody
Anti-Progesterone Receptor Complex P23 antibody
Anti-Telomerase-Binding Protein P23 antibody
Anti-PTGES3 antibody
Anti-P23 antibody
Anti-TEBP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance