• Western blot analysis of lysates from K562 cells treated with UV 30', using PBK/TOPK (Phospho-Thr9) Antibody. The lane on the right is blocked with the phospho peptide.
  • Western blot analysis of 293T cells using Phospho-PBK (T9) Polyclonal Antibody diluted at 1：500

Anti-Phospho-PBK-Thr9 antibody (1-50 aa) (STJ90490)

SKU:
STJ90490

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Lymphokine-activated killer T-cell-originated protein kinase-Thr9 (1-50 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PBK
Gene ID: 55872
Uniprot ID: TOPK_HUMAN
Immunogen Region: 1-50 aa
Specificity: Phospho-PBK (T9) Polyclonal Antibody detects endogenous levels of PBK protein only when phosphorylated at T9.
Immunogen: The antiserum was produced against synthesized peptide derived from the human PBK/TOPK around the phosphorylation site of Thr9 at the amino acid range 1-50
Post Translational Modifications Phosphorylated.in a cell-cycle dependent manner at mitosis.
Function Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.
Protein Name Lymphokine-Activated Killer T-Cell-Originated Protein Kinase
Cancer/Testis Antigen 84
Ct84
Mapkk-Like Protein Kinase
Nori-3
Pdz-Binding Kinase
Spermatogenesis-Related Protein Kinase
Spk
T-Lak Cell-Originated Protein Kinase
Alternative Antibody Names Anti-Lymphokine-Activated Killer T-Cell-Originated Protein Kinase antibody
Anti-Cancer/Testis Antigen 84 antibody
Anti-Ct84 antibody
Anti-Mapkk-Like Protein Kinase antibody
Anti-Nori-3 antibody
Anti-Pdz-Binding Kinase antibody
Anti-Spermatogenesis-Related Protein Kinase antibody
Anti-Spk antibody
Anti-T-Lak Cell-Originated Protein Kinase antibody
Anti-PBK antibody
Anti-TOPK antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance