• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using NudC (Phospho-Ser326) Antibody. The picture on the right is blocked with the phospho peptide.
  • Western blot analysis of lysates from rat brain, using NudC (Phospho-Ser326) Antibody. The lane on the right is blocked with the phospho peptide.
  • Western blot analysis of JK cells using Phospho-NUDC (S326) Polyclonal Antibody

Anti-Phospho-NUDC-Ser326 antibody (282-331 aa) (STJ90986)

SKU:
STJ90986

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Nuclear migration protein nudC-Ser326 (282-331 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NUDC
Gene ID: 10726
Uniprot ID: NUDC_HUMAN
Immunogen Region: 282-331 aa
Specificity: Phospho-NUDC (S326) Polyclonal Antibody detects endogenous levels of NUDC protein only when phosphorylated at S326.
Immunogen: The antiserum was produced against synthesized peptide derived from the human NudC around the phosphorylation site of Ser326 at the amino acid range 282-331
Post Translational Modifications Reversibly phosphorylated on serine residues during the M phase of the cell cycle. Phosphorylation on Ser-274 and Ser-326 is necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Phosphorylated by PLK and other kinases.
Function Plays a role in neurogenesis and neuronal migration. Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.
Protein Name Nuclear Migration Protein Nudc
Nuclear Distribution Protein C Homolog
Database Links Reactome: R-HSA-141444
Reactome: R-HSA-2467813
Reactome: R-HSA-2500257
Reactome: R-HSA-5663220
Reactome: R-HSA-68877
Reactome: R-HSA-9648025
Reactome: R-HSA-9696270
Cellular Localisation Cytoplasm
Cytoskeleton
Nucleus
Spindle
Midbody
In A Filamentous Pattern Adjacent To The Nucleus Of Migrating Cerebellar Granule Cells
Colocalizes With Tubulin And Dynein And With The Microtubule Organizing Center
Distributed Throughout The Cytoplasm Of Non-Migrating Cells
A Small Proportion Is Nuclear
In A Punctate Pattern
Localizes To The Mitotic Spindle In A Eml4-Dependent Manner
Alternative Antibody Names Anti-Nuclear Migration Protein Nudc antibody
Anti-Nuclear Distribution Protein C Homolog antibody
Anti-NUDC antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance