| Host: | Rabbit |
| Applications: | WB/ICC |
| Reactivity: | Chicken/Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phospho-Myosin Light Chain-Ser-19 is suitable for use in Western Blot and Immunocytochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Purification: | Antigen Affinity Purified |
| Dilution Range: | WB 1:1000ICC 1:100 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MYL12A |
| Gene ID: | 10627 |
| Uniprot ID: | ML12A_HUMAN |
| Specificity: | This antibody was cross-adsorbed to MLC (a.a. 11-22) then affinity purified using phospho-MLC (Ser-19) peptide (without carrier). The antibody detects a 20 kDa* band corresponding to the molecular weight of myosin light chain in human A431 treated wi |
| Immunogen: | Phospho-MLC (Ser-19) synthetic peptide (coupled to KLH) corresponds to amino acid residues surrounding Ser-19 in human myosin regulatory light chain 12A (Myl12A). This peptide sequence is highly conserved in human, rat, mouse, chicken, and zebrafish |
| Function | Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. |
| Protein Name | Myosin Regulatory Light Chain 12aEpididymis Secretory Protein Li 24Hel-S-24Mlc-2bMyosin RlcMyosin Regulatory Light Chain 2 - NonsarcomericMyosin Regulatory Light Chain Mrlc3 |
| Database Links | Reactome: R-HSA-3928664Reactome: R-HSA-445355 |
| Alternative Antibody Names | Anti-Myosin Regulatory Light Chain 12a antibodyAnti-Epididymis Secretory Protein Li 24 antibodyAnti-Hel-S-24 antibodyAnti-Mlc-2b antibodyAnti-Myosin Rlc antibodyAnti-Myosin Regulatory Light Chain 2 - Nonsarcomeric antibodyAnti-Myosin Regulatory Light Chain Mrlc3 antibodyAnti-MYL12A antibodyAnti-MLCB antibodyAnti-MRLC3 antibodyAnti-RLC antibody |
Information sourced from Uniprot.org