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Anti-Phospho-MYC-Ser62 antibody (31-80 aa) (STJ91021)

Western blot analysis of lysates from 293 cells treated with Forskolin 40nM 30', using Myc (Phospho-Ser62) Antibody. The lane on the right is blocked with the phospho peptide.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using Myc (Phospho-Ser62) Antibody. The picture on the right is blocked with the phospho peptide.
Western blot analysis of 293 cells using Phospho-c-Myc (S62) Polyclonal Antibody diluted at 1：1000
Immunofluorescence analysis of HeLa cells treated with Forskolin 40nM 30', using Myc (Phospho-Ser62) Antibody. The picture on the right is blocked with the phospho peptide.
Western blot analysis of various cells using Phospho-c-Myc (S62) Polyclonal Antibody diluted at 1：1000

Anti-Phospho-MYC-Ser62 antibody (31-80 aa) (STJ91021)

SKU:

STJ91021

£46.00 - £226.00

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Phospho-Myc proto-oncogene protein-Ser62 (31-80 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:40000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	MYC
Gene ID:	4609
Uniprot ID:	MYC_HUMAN
Immunogen Region:	31-80 aa
Specificity:	Phospho-c-Myc (S62) Polyclonal Antibody detects endogenous levels of c-Myc protein only when phosphorylated at S62.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human Myc around the phosphorylation site of Ser62 at the amino acid range 31-80

Function	Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CACGATG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release. Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform.
Protein Name	Myc Proto-Oncogene Protein Class E Basic Helix-Loop-Helix Protein 39 Bhlhe39 Proto-Oncogene C-Myc Transcription Factor P64
Database Links	Reactome: R-HSA-1362277 Reactome: R-HSA-201556 Reactome: R-HSA-2122947 Reactome: R-HSA-2173796 Reactome: R-HSA-2644606 Reactome: R-HSA-2894862 Reactome: R-HSA-4411364 Reactome: R-HSA-5687128 Reactome: R-HSA-5689880 Reactome: R-HSA-6785807 Reactome: R-HSA-69202 Reactome: R-HSA-69656 Reactome: R-HSA-8866911 Reactome: R-HSA-8951430 Reactome: R-HSA-9018519 Reactome: R-HSA-9616222 Reactome: R-HSA-9818749
Cellular Localisation	Nucleus Nucleoplasm Nucleolus
Alternative Antibody Names	Anti-Myc Proto-Oncogene Protein antibody Anti-Class E Basic Helix-Loop-Helix Protein 39 antibody Anti-Bhlhe39 antibody Anti-Proto-Oncogene C-Myc antibody Anti-Transcription Factor P64 antibody Anti-MYC antibody Anti-BHLHE39 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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