Anti-Phospho-MLC-2-Thr17/S18 antibody (5-54 aa) (STJ91117)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human MLC-2 around the phosphorylation site of Thr17 and Ser18 at the amino acid range 5-54
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Myosin regulatory light chain 12A and Myosin regulatory light chain 12B and Myosin regulatory light polypeptide 9-Thr17/S18 (5-54 aa) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYL9MYL12B1039810391010627 |
| Uniprot ID | MYL9_HUMANML12B_HUMANML12A_HUMAN< |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human MLC-2 around the phosphorylation site of Thr17 and Ser18 at the amino acid range 5-54 |
| Immunogen Region | 5-54 aa |
| Specificity | Phospho-MLC-2 (T17/S18) Polyclonal Antibody detects endogenous levels of MLC-2 protein only when phosphorylated at T17/S18. |
Additional Info
| Function | Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. |
| Protein Name | Myosin Regulatory Light Chain 12aEpididymis Secretory Protein Li 24Hel-S-24Mlc-2bMyosin RlcMyosin Regulatory Light Chain 2 - NonsarcomericMyosin Regulatory Light Chain Mrlc3 |
| Database Links | Reactome: R-HSA-3928664Reactome: R-HSA-445355 |
| Alternative Antibody Names | Anti-Myosin Regulatory Light Chain 12a antibodyAnti-Epididymis Secretory Protein Li 24 antibodyAnti-Hel-S-24 antibodyAnti-Mlc-2b antibodyAnti-Myosin Rlc antibodyAnti-Myosin Regulatory Light Chain 2 - Nonsarcomeric antibodyAnti-Myosin Regulatory Light Chain Mrlc3 antibodyAnti-MYL12A antibodyAnti-MLCB antibodyAnti-MRLC3 antibodyAnti-RLC antibody |
Information sourced from Uniprot.org