• Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

Anti-Phospho-MAX-Ser2 antibody (1-50 aa) (STJ91169)

SKU:
STJ91169

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Protein max-Ser2 (1-50 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MAX
Gene ID: 4149
Uniprot ID: MAX_HUMAN
Immunogen Region: 1-50 aa
Specificity: Phospho-Max (S2) Polyclonal Antibody detects endogenous levels of Max protein only when phosphorylated at S2.
Immunogen: The antiserum was produced against synthesized peptide derived from the human MAX around the phosphorylation site of Ser2 at the amino acid range 1-50
Post Translational Modifications Reversible lysine acetylation might regulate the nuclear-cytoplasmic shuttling of specific Max complexes.
Function Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CACGATG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements.
Protein Name Protein Max
Class D Basic Helix-Loop-Helix Protein 4
Bhlhd4
Myc-Associated Factor X
Database Links Reactome: R-HSA-1362277
Reactome: R-HSA-69202
Reactome: R-HSA-69656
Reactome: R-HSA-8953750
Cellular Localisation Nucleus
Cell Projection
Dendrite
Alternative Antibody Names Anti-Protein Max antibody
Anti-Class D Basic Helix-Loop-Helix Protein 4 antibody
Anti-Bhlhd4 antibody
Anti-Myc-Associated Factor X antibody
Anti-MAX antibody
Anti-BHLHD4 antibody

Information sourced from Uniprot.org

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