• Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-Phospho-LCP1-Tyr28 antibody (STJ196347)

SKU:
STJ196347

$64.80 - $340.20
Current Stock:
Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Plastin-2-Tyr28 is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LCP1
Gene ID: 3936
Uniprot ID: PLSL_HUMAN
Specificity: This antibody detects endogenous levels of Human LCP1 (phospho-Tyr28)
Immunogen: Synthesized phosho peptide around human LCP1 (Tyr28)
Post Translational Modifications Phosphorylated on a serine residue in response to costimulation through TCR/CD3 and CD2 or CD28. Serine phosphorylation promotes association with the actin cytoskeleton and targeting to peripheral cell projections.
Function Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69.
Protein Name Plastin-2
L-Plastin
Lc64p
Lymphocyte Cytosolic Protein 1
Lcp-1
Database Links Reactome: R-HSA-8950505
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Junction
Cell Projection
Ruffle Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Relocalizes To The Immunological Synapse Between Peripheral Blood T-Lymphocytes And Antibody-Presenting Cells In Response To Costimulation Through Tcr/Cd3 And Cd2 Or Cd28
Associated With The Actin Cytoskeleton At Membrane Ruffles
Relocalizes To Actin-Rich Cell Projections Upon Serine Phosphorylation
Alternative Antibody Names Anti-Plastin-2 antibody
Anti-L-Plastin antibody
Anti-Lc64p antibody
Anti-Lymphocyte Cytosolic Protein 1 antibody
Anti-Lcp-1 antibody
Anti-LCP1 antibody
Anti-PLS2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance