| Host: |
Rabbit |
| Applications: |
WB/IHC/IF/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Phospho-Kinesin-like protein KIF20A-Ser528 (501-550 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KIF20A |
| Gene ID: |
10112 |
| Uniprot ID: |
KI20A_HUMAN |
| Immunogen Region: |
501-550 aa |
| Specificity: |
Phospho-KIF20A (S528) Polyclonal Antibody detects endogenous levels of KIF20A protein only when phosphorylated at S528. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human KIF20A around the phosphorylation site of Ser528 at the amino acid range 501-550 |
| Function | Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. |
| Protein Name | Kinesin-Like Protein Kif20aGg10_2Mitotic Kinesin-Like Protein 2Mklp2Rab6-Interacting Kinesin-Like ProteinRabkinesin-6 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-6811434Reactome: R-HSA-68884Reactome: R-HSA-983189 |
| Cellular Localisation | Golgi ApparatusCytoplasmCytoskeletonSpindleLocalizes To The Spindle Midzone During Anaphase And Telophase |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif20a antibodyAnti-Gg10_2 antibodyAnti-Mitotic Kinesin-Like Protein 2 antibodyAnti-Mklp2 antibodyAnti-Rab6-Interacting Kinesin-Like Protein antibodyAnti-Rabkinesin-6 antibodyAnti-KIF20A antibodyAnti-MKLP2 antibodyAnti-RAB6KIFL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
