• Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-Phospho-KIF1B-Ser1487 antibody (STJ196344)

SKU:
STJ196344

£48.00 - £252.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Kinesin-like protein KIF1B-Ser1487 is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KIF1B
Gene ID: 23095
Uniprot ID: KIF1B_HUMAN
Specificity: This antibody detects endogenous levels of Human KIF1B (phospho-Ser1487)
Immunogen: Synthesized phosho peptide around human KIF1B (Ser1487)
Function Has a plus-end-directed microtubule motor activity and functions as a motor for transport of vesicles and organelles along microtubules. Isoform 2: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde synaptic vesicle transport along axonal microtubules from the cell body to the presynapse in neuronal cells. Functions as a downstream effector in a developmental apoptotic pathway that is activated when nerve growth factor (NGF) becomes limiting for neuronal progenitor cells. Isoform 3: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde transport of mitochondria.
Protein Name Kinesin-Like Protein Kif1b
Klp
Database Links Reactome: R-HSA-6811434
Reactome: R-HSA-983189
Cellular Localisation Cytoplasm
Cytoskeleton
Has A Plus-End-Directed Microtubule Motor Activity And Therefore Associates With Microtubules
Isoform 2: Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle Membrane
Associates With Synaptic Vesicles And Mediates Their Anterograde Transport Along Axonal Microtubules
Isoform 3: Mitochondrion
Associates With Mitochondria And Mediates Their Movement Along Microtubules
Alternative Antibody Names Anti-Kinesin-Like Protein Kif1b antibody
Anti-Klp antibody
Anti-KIF1B antibody
Anti-KIAA0591 antibody
Anti-KIAA1448 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance