• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using HSP20 (Phospho-Ser16) Antibody. The picture on the right is blocked with the phospho peptide.
  • Immunofluorescence analysis of HeLa cells, using HSP20 (Phospho-Ser16) Antibody. The picture on the right is blocked with the phospho peptide.

Anti-Phospho-HSPB6-Ser16 antibody (5-54 aa) (STJ91290)

SKU:
STJ91290

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Heat shock protein beta-6-Ser16 (5-54 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HSPB6
Gene ID: 126393
Uniprot ID: HSPB6_HUMAN
Immunogen Region: 5-54 aa
Specificity: Phospho-HSP20 (S16) Polyclonal Antibody detects endogenous levels of HSP20 protein only when phosphorylated at S16.
Immunogen: The antiserum was produced against synthesized peptide derived from the human HSP20 around the phosphorylation site of Ser16 at the amino acid range 5-54
Function Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity.
Protein Name Heat Shock Protein Beta-6
Hspb6
Heat Shock 20 Kda-Like Protein P20
Cellular Localisation Cytoplasm
Nucleus
Secreted
Translocates To Nuclear Foci During Heat Shock
Alternative Antibody Names Anti-Heat Shock Protein Beta-6 antibody
Anti-Hspb6 antibody
Anti-Heat Shock 20 Kda-Like Protein P20 antibody
Anti-HSPB6 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance