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Anti-Phospho-GRIN1-Ser890 antibody (856-905 aa) (STJ91295)

Immunofluorescence analysis of A549 cells, using NMDAR1 (Phospho-Ser890) Antibody. The picture on the right is blocked with the phospho peptide.
Immunohistochemistry analysis of paraffin-embedded human brain, using NMDAR1 (Phospho-Ser890) Antibody. The picture on the right is blocked with the phospho peptide.
Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

Anti-Phospho-GRIN1-Ser890 antibody (856-905 aa) (STJ91295)

SKU:

STJ91295

£46.00 - £226.00

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	IHC/IF/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Phospho-Glutamate receptor ionotropic, NMDA 1-Ser890 (856-905 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:40000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	GRIN1
Gene ID:	2902
Uniprot ID:	NMDZ1_HUMAN
Immunogen Region:	856-905 aa
Specificity:	Phospho-NMDA Zeta 1 (S890) Polyclonal Antibody detects endogenous levels of NMDA Zeta 1 protein only when phosphorylated at S890.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human NMDAR1 around the phosphorylation site of Ser890 at the amino acid range 856-905

Function	Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition.
Protein Name	Glutamate Receptor Ionotropic - Nmda 1 Glun1 Glutamate Nmda Receptor Subunit Zeta-1 N-Methyl-D-Aspartate Receptor Subunit Nr1 Nmd-R1
Database Links	Reactome: R-HSA-3928662 Reactome: R-HSA-438066 Reactome: R-HSA-442982 Reactome: R-HSA-5673001 Reactome: R-HSA-6794361 Reactome: R-HSA-8849932 Reactome: R-HSA-9609736 Reactome: R-HSA-9617324 Reactome: R-HSA-9620244
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Postsynaptic Cell Membrane Postsynaptic Density Enriched In Postsynaptic Plasma Membrane And Postsynaptic Densities
Alternative Antibody Names	Anti-Glutamate Receptor Ionotropic - Nmda 1 antibody Anti-Glun1 antibody Anti-Glutamate Nmda Receptor Subunit Zeta-1 antibody Anti-N-Methyl-D-Aspartate Receptor Subunit Nr1 antibody Anti-Nmd-R1 antibody Anti-GRIN1 antibody Anti-NMDAR1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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