Anti-Phospho-GFAP-Ser38 antibody (11-60 aa) (STJ91108)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human GFAP around the phosphorylation site of Ser38 at the amino acid range 11-60
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Glial fibrillary acidic protein-Ser38 (11-60 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GFAP |
| Gene ID | 2670 |
| Uniprot ID | GFAP_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human GFAP around the phosphorylation site of Ser38 at the amino acid range 11-60 |
| Immunogen Region | 11-60 aa |
| Specificity | Phospho-GFAP (S38) Polyclonal Antibody detects endogenous levels of GFAP protein only when phosphorylated at S38. |
Additional Info
| Post Translational Modifications | Phosphorylated by PKN1. |
| Function | GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. |
| Protein Name | Glial Fibrillary Acidic ProteinGfap |
| Database Links | Reactome: R-HSA-1251985Reactome: R-HSA-9613829 |
| Cellular Localisation | CytoplasmAssociated With Intermediate Filaments |
| Alternative Antibody Names | Anti-Glial Fibrillary Acidic Protein antibodyAnti-Gfap antibodyAnti-GFAP antibody |
Information sourced from Uniprot.org