• Western blot analysis of Jurkat cells using Phospho-4.1R (Y660) Polyclonal Antibody
  • Western blot analysis of lysates from HepG2 cells treated with PMA 125ng/ml 30', using EPB41 (Phospho-Tyr660/418) Antibody. The lane on the right is blocked with the phospho peptide.
  • Western blot analysis of JK cells using Phospho-4.1R (Y660) Polyclonal Antibody

Anti-Phospho-EPB41-Tyr660 antibody (626-675 aa) (STJ90628)

SKU:
STJ90628

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Protein 4.1-Tyr660 (626-675 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EPB41
Gene ID: 2035
Uniprot ID: EPB41_HUMAN
Immunogen Region: 626-675 aa
Specificity: Phospho-4.1R (Y660) Polyclonal Antibody detects endogenous levels of 4.1R protein only when phosphorylated at Y660.
Immunogen: The antiserum was produced against synthesized peptide derived from the human EPB41 around the phosphorylation site of Tyr660/418 at the amino acid range 626-675
Function Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase.
Protein Name Protein 4.1
P4.1
4.1r
Band 4.1
Epb4.1
Erythrocyte Membrane Protein Band 4.1
Database Links Reactome: R-HSA-6794361
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Cortex
Nucleus
Alternative Antibody Names Anti-Protein 4.1 antibody
Anti-P4.1 antibody
Anti-4.1r antibody
Anti-Band 4.1 antibody
Anti-Epb4.1 antibody
Anti-Erythrocyte Membrane Protein Band 4.1 antibody
Anti-EPB41 antibody
Anti-E41P antibody

Information sourced from Uniprot.org

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