| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | Dok7 |
| Gene ID: | 231134 |
| Uniprot ID: | DOK7_MOUSE |
| Specificity: | A phospho specific peptide corresponding to residues surrounding Y406 of Mouse DOK7 |
| Function | Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK. |
| Protein Name | Protein Dok-7Downstream Of Tyrosine Kinase 7 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinSynapseAccumulates At Neuromuscular Junctions |
| Alternative Antibody Names | Anti-Protein Dok-7 antibodyAnti-Downstream Of Tyrosine Kinase 7 antibodyAnti-Dok7 antibody |
Information sourced from Uniprot.org