| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phospho-Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide-Tyr139 (105-154 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DAPP1 |
| Gene ID: | 27071 |
| Uniprot ID: | DAPP1_HUMAN |
| Immunogen Region: | 105-154 aa |
| Specificity: | Phospho-BAM32 (Y139) Polyclonal Antibody detects endogenous levels of BAM32 protein only when phosphorylated at Y139. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human DAPP1 around the phosphorylation site of Tyr139 at the amino acid range 105-154 |
| Post Translational Modifications | Phosphorylated on tyrosine residues. |
| Function | May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K. |
| Protein Name | Dual Adapter For Phosphotyrosine And 3-Phosphotyrosine And 3-PhosphoinositideHdapp1B Lymphocyte Adapter Protein Bam32B-Cell Adapter Molecule Of 32 Kda |
| Database Links | Reactome: R-HSA-983695 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinMembrane-Associated After Cell Stimulation Leading To Its Translocation |
| Alternative Antibody Names | Anti-Dual Adapter For Phosphotyrosine And 3-Phosphotyrosine And 3-Phosphoinositide antibodyAnti-Hdapp1 antibodyAnti-B Lymphocyte Adapter Protein Bam32 antibodyAnti-B-Cell Adapter Molecule Of 32 Kda antibodyAnti-DAPP1 antibodyAnti-BAM32 antibodyAnti-HSPC066 antibody |
Information sourced from Uniprot.org