Anti-Phospho-Cdc25C-Ser216 antibody [PT1382R] (STJA0040271)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgGk
General Information
| Short Description | Rabbit monoclonal anti-Phospho-M-Phase Inducer Phosphatase 3-Ser216 for use in WB, IHC, IF, IP and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/IP/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | PT1382R |
| Isotype | IgGk |
| Conjugation | Unconjugated |
| Purification | Protein A |
| Dilution Range | IHC 1:200-1:1000WB 1:500-1:2000IF 1:200-1:1000ELISA 1:5000-1:20000IP 1:50-1:200 |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDC25C |
| Gene ID | 995 |
| Uniprot ID | MPIP3_HUMAN |
| Specificity | Cdc25C (Phospho Ser216) Antibody detects endogenous levels of Cdc25C protein only when phosphorylated at S216.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) |
Additional Info
| Function | Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity. |
| Protein Name | M-Phase Inducer Phosphatase 3Dual Specificity Phosphatase Cdc25c |
| Database Links | Reactome: R-HSA-156711Reactome: R-HSA-176187Reactome: R-HSA-5625740Reactome: R-HSA-6804114Reactome: R-HSA-6804115Reactome: R-HSA-69273Reactome: R-HSA-75035Reactome: R-HSA-8862803 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-M-Phase Inducer Phosphatase 3 antibodyAnti-Dual Specificity Phosphatase Cdc25c antibodyAnti-CDC25C antibody |
Information sourced from Uniprot.org