Anti-Phospho-CCNE2-Thr392 antibody (355-404 aa) (STJ91333)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human Cyclin E2 around the phosphorylation site of Thr392 at the amino acid range 355-404
General Information
| Short Description | Rabbit polyclonal anti-Phospho-G1/S-specific cyclin-E2-Thr392 (355-404 aa) for use in IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IF 1:200-1:1000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCNE2 |
| Gene ID | 9134 |
| Uniprot ID | CCNE2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human Cyclin E2 around the phosphorylation site of Thr392 at the amino acid range 355-404 |
| Immunogen Region | 355-404 aa |
| Specificity | Phospho-Cyclin E2 (T392) Polyclonal Antibody detects endogenous levels of Cyclin E2 protein only when phosphorylated at T392. |
Additional Info
| Post Translational Modifications | Phosphorylation by CDK2 triggers its release from CDK2 and degradation via the ubiquitin proteasome pathway. Lactylated at Lys-348. Delactylated by SIRT3. |
| Function | Essential for the control of the cell cycle at the late G1 and early S phase. |
| Protein Name | G1/S-Specific Cyclin-E2 |
| Database Links | Reactome: R-HSA-1538133Reactome: R-HSA-187577Reactome: R-HSA-2559586Reactome: R-HSA-390471Reactome: R-HSA-6804116Reactome: R-HSA-69017Reactome: R-HSA-69200Reactome: R-HSA-69202Reactome: R-HSA-69231Reactome: R-HSA-69563Reactome: R-HSA-9661069 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-G1/S-Specific Cyclin-E2 antibodyAnti-CCNE2 antibody |
Information sourced from Uniprot.org