Anti-Phospho-CACNB2 antibody (600-655) {Biotin} (STJ502191)

Name: Anti-Phospho-CACNB2 antibody (600-655) {Biotin} (STJ502191)
SKU: STJ502191-100
Price: 761.07 USD
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationBiotin

IsotypeIgG

ImmunogenSynthetic peptide taken within amino acid region 600-655 on rat CACNB2 protein.

STJ502191-100

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Short Description	Rabbit polyclonal antibody anti-Phospho-CACNB2 (600-655) is suitable for use in ELISA and Western Blot research applications.
Applications	ELISA/WB
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Biotin
Concentration	0.6 µg/µl
Purification	Affinity Purified
Dilution Range	WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000
Formulation	Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage Instruction	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol	Cacnb2
Gene ID	116600
Uniprot ID	CACB2_RAT
Immunogen	Synthetic peptide taken within amino acid region 600-655 on rat CACNB2 protein.
Immunogen Region	600-655

Tissue Specificity	Highly expressed in heart and brain, and at lower levels in lung.
Post Translational Modifications	Regulated through phosphorylation at Thr-549 by CaMK2D.
Function	Beta subunit of voltage-dependent calcium channels which contributes to the function of the calcium channel by increasing peak calcium current. Plays a role in shifting voltage dependencies of activation and inactivation of the channel. May modulate G protein inhibition. May contribute to beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force. Involved in membrane targeting of the alpha-1 subunit CACNA1C.
Protein Name	Voltage-Dependent L-Type Calcium Channel Subunit Beta-2 Cab2 Calcium Channel Voltage-Dependent Subunit Beta 2
Database Links	Reactome: R-RNO-112308 Reactome: -RNO-422356 Reactome: -RNO-5576892 Reactome: -RNO-5576893
Cellular Localisation	Cell Membrane Sarcolemma Peripheral Membrane Protein Cytoplasmic Side
Alternative Antibody Names	Anti-Voltage-Dependent L-Type Calcium Channel Subunit Beta-2 antibody Anti-Cab2 antibody Anti-Calcium Channel Voltage-Dependent Subunit Beta 2 antibody Anti-Cacnb2 antibody Anti-Cacnlb2 antibody

Information sourced from Uniprot.org