| Host: |
Rabbit |
| Applications: |
IHC/IF/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Phospho-C5a anaphylatoxin chemotactic receptor 1-Ser338 (301-350 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
C5AR1 |
| Gene ID: |
728 |
| Uniprot ID: |
C5AR1_HUMAN |
| Immunogen Region: |
301-350 aa |
| Specificity: |
Phospho-CD88 (S338) Polyclonal Antibody detects endogenous levels of CD88 protein only when phosphorylated at S338. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human CD88/C5aR around the phosphorylation site of Ser338 at the amino acid range 301-350 |
| Function | Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. |
| Protein Name | C5a Anaphylatoxin Chemotactic Receptor 1C5a Anaphylatoxin Chemotactic ReceptorC5a-RC5arCd Antigen Cd88 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594Reactome: R-HSA-6798695Reactome: R-HSA-977606 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmic VesiclePhosphorylated C5ar Colocalizes With Arrb1 And Arrb2 In Cytoplasmic Vesicles |
| Alternative Antibody Names | Anti-C5a Anaphylatoxin Chemotactic Receptor 1 antibodyAnti-C5a Anaphylatoxin Chemotactic Receptor antibodyAnti-C5a-R antibodyAnti-C5ar antibodyAnti-Cd Antigen Cd88 antibodyAnti-C5AR1 antibodyAnti-C5AR antibodyAnti-C5R1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
