| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phospho-Bcl-2-interacting killer-Thr33 (18-67 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BIK |
| Gene ID: | 638 |
| Uniprot ID: | BIK_HUMAN |
| Immunogen Region: | 18-67 aa |
| Specificity: | Phospho-NBK (T33) Polyclonal Antibody detects endogenous levels of NBK protein only when phosphorylated at T33. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human BIK around the phosphorylation site of Thr33 at the amino acid range 18-67 |
| Function | Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX. |
| Protein Name | Bcl-2-Interacting KillerApoptosis Inducer NbkBip1Bp4 |
| Cellular Localisation | Endomembrane SystemSingle-Pass Membrane ProteinMitochondrion MembraneAround The Nuclear EnvelopeAnd In Cytoplasmic Membranes |
| Alternative Antibody Names | Anti-Bcl-2-Interacting Killer antibodyAnti-Apoptosis Inducer Nbk antibodyAnti-Bip1 antibodyAnti-Bp4 antibodyAnti-BIK antibodyAnti-NBK antibody |
Information sourced from Uniprot.org