| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phospho-Bcl-2-interacting killer-Ser35 is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BIK |
| Gene ID: | 638 |
| Uniprot ID: | BIK_HUMAN |
| Specificity: | Phospho-NBK (S35) Polyclonal Antibody detects endogenous levels of NBK protein only when phosphorylated at S35. |
| Immunogen: | Synthesized phospho-peptide around the phosphorylation site of human NBK (phospho Ser35) |
| Function | Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX. |
| Protein Name | Bcl-2-Interacting KillerApoptosis Inducer NbkBip1Bp4 |
| Database Links | |
| Cellular Localisation | Endomembrane SystemSingle-Pass Membrane ProteinMitochondrion MembraneAround The Nuclear EnvelopeAnd In Cytoplasmic Membranes |
| Alternative Antibody Names | Anti-Bcl-2-Interacting Killer antibodyAnti-Apoptosis Inducer Nbk antibodyAnti-Bip1 antibodyAnti-Bp4 antibodyAnti-BIK antibodyAnti-NBK antibody |
Information sourced from Uniprot.org
