• Western blot of mouse testicular lysate showing specific immunolabeling of the ~86 kDa ATRIP protein phosphorylated at Ser239 in the first lane (-). Phosphospecificity is shown in the second lane (+) where the immunolabeling is completely eliminated by lysate treatment with lambda phosphatase ( Lambda-Ptase, 800 units/1mg protein for 30 minutes).

Anti-Phospho-ATRIP-Ser239 antibody (STJA0003585)

SKU:
STJA0003585-100

£442.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse/Bovine/Human/Non-Human Primates/Sheep
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-ATRIP-Ser239 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol.
Purification: This antibody was antigen affinity purified from pooled serum.
Dilution Range: WB 1:500
IHC
ICC
IP
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ATRIP
Gene ID: 84126
Uniprot ID: ATRIP_HUMAN
Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser239 conjugated to KLH.
Tissue Specificity Ubiquitous.
Post Translational Modifications Phosphorylated by ATR.
Function Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.
Protein Name Atr-Interacting Protein
Atm And Rad3-Related-Interacting Protein
Database Links Reactome: R-HSA-176187
Reactome: R-HSA-5685938
Reactome: R-HSA-5693607
Reactome: R-HSA-5693616
Reactome: R-HSA-6783310
Reactome: R-HSA-6804756
Reactome: R-HSA-69473
Reactome: R-HSA-9709570
Cellular Localisation Nucleus
Redistributes To Discrete Nuclear Foci Upon Dna Damage
Alternative Antibody Names Anti-Atr-Interacting Protein antibody
Anti-Atm And Rad3-Related-Interacting Protein antibody
Anti-ATRIP antibody
Anti-AGS1 antibody

Information sourced from Uniprot.org

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