| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Mouse/Bovine/Human/Non-Human Primates/Sheep |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phospho-ATRIP-Ser239 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
| Purification: | This antibody was antigen affinity purified from pooled serum. |
| Dilution Range: | WB 1:500 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ATRIP |
| Gene ID: | 84126 |
| Uniprot ID: | ATRIP_HUMAN |
| Immunogen: | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser239 conjugated to KLH. |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Phosphorylated by ATR. |
| Function | Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein. |
| Protein Name | Atr-Interacting Protein Atm And Rad3-Related-Interacting Protein |
| Database Links | Reactome: R-HSA-176187 Reactome: R-HSA-5685938 Reactome: R-HSA-5693607 Reactome: R-HSA-5693616 Reactome: R-HSA-6783310 Reactome: R-HSA-6804756 Reactome: R-HSA-69473 Reactome: R-HSA-9709570 |
| Cellular Localisation | Nucleus Redistributes To Discrete Nuclear Foci Upon Dna Damage |
| Alternative Antibody Names | Anti-Atr-Interacting Protein antibody Anti-Atm And Rad3-Related-Interacting Protein antibody Anti-ATRIP antibody Anti-AGS1 antibody |
Information sourced from Uniprot.org