Anti-Phospho-ATRIP-Ser224 antibody (190-239 aa) (STJ90973)

SKU:
STJ90973
£49.00 - £261.00
Processing The item has been added

Short Description :Rabbit polyclonal anti-Phospho-ATR-interacting protein-Ser224 (190-239 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC/IF/ELISA
Host:Rabbit
Reactivity:Human/Rat/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:ATRIP
Gene ID:84126
Uniprot ID:ATRIP_HUMAN
Immunogen:The antiserum was produced against synthesized peptide derived from the human ATRIP around the phosphorylation site of Ser224 at the amino acid range 190-239
Immunogen Region:190-239 aa
Specificity:Phospho-ATRIP (S224) Polyclonal Antibody detects endogenous levels of ATRIP protein only when phosphorylated at S224.
Post Translational Modifications Phosphorylated by ATR.
Function Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.
Protein Name Atr-Interacting Protein
Atm And Rad3-Related-Interacting Protein
Database Links Reactome: R-HSA-176187
Reactome: R-HSA-5685938
Reactome: R-HSA-5693607
Reactome: R-HSA-5693616
Reactome: R-HSA-6783310
Reactome: R-HSA-6804756
Reactome: R-HSA-69473
Reactome: R-HSA-9709570
Cellular Localisation Nucleus
Redistributes To Discrete Nuclear Foci Upon Dna Damage
Alternative Antibody Names Anti-Atr-Interacting Protein antibody
Anti-Atm And Rad3-Related-Interacting Protein antibody
Anti-ATRIP antibody
Anti-AGS1 antibody

Information sourced from Uniprot.org