| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phospho-Alpha-adducin and Beta-adducin-Ser726/713 (688-737 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADD2 ADD1 |
| Gene ID: | 119 118 |
| Uniprot ID: | ADDB_HUMAN ADDA_HUMAN |
| Immunogen Region: | 688-737 aa |
| Specificity: | Phospho-Adducin Alpha/Beta (S726/713) Polyclonal Antibody detects endogenous levels of Adducin Alpha/Beta protein only when phosphorylated at S726/713. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ADD1 around the phosphorylation site of Ser726 at the amino acid range 688-737 |
| Function | Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin. |
| Protein Name | Alpha-Adducin Erythrocyte Adducin Subunit Alpha |
| Database Links | Reactome: R-HSA-264870 Reactome: R-HSA-381038 Reactome: R-HSA-5223345 |
| Cellular Localisation | Cytoplasm Cytoskeleton Cell Membrane Peripheral Membrane Protein Cytoplasmic Side |
| Alternative Antibody Names | Anti-Alpha-Adducin antibody Anti-Erythrocyte Adducin Subunit Alpha antibody Anti-ADD1 antibody Anti-ADDA antibody |
Information sourced from Uniprot.org