Anti-Phospho-ADD1-Thr445 antibody (411-460 aa) (STJ91115)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ADD1 around the phosphorylation site of Thr445 at the amino acid range 411-460
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Alpha-adducin-Thr445 (411-460 aa) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADD1 |
| Gene ID | 118 |
| Uniprot ID | ADDA_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ADD1 around the phosphorylation site of Thr445 at the amino acid range 411-460 |
| Immunogen Region | 411-460 aa |
| Specificity | Phospho-Adducin Alpha (T445) Polyclonal Antibody detects endogenous levels of Adducin Alpha protein only when phosphorylated at T445. |
Additional Info
| Function | Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin. |
| Protein Name | Alpha-AdducinErythrocyte Adducin Subunit Alpha |
| Database Links | Reactome: R-HSA-264870Reactome: R-HSA-381038Reactome: R-HSA-5223345 |
| Cellular Localisation | CytoplasmCytoskeletonCell MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Alpha-Adducin antibodyAnti-Erythrocyte Adducin Subunit Alpha antibodyAnti-ADD1 antibodyAnti-ADDA antibody |
Information sourced from Uniprot.org