| Short Description : | Rabbit polyclonal anti-Phospho-Alpha-adducin-Thr445 (411-460 aa) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADD1 |
| Gene ID: | 118 |
| Uniprot ID: | ADDA_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ADD1 around the phosphorylation site of Thr445 at the amino acid range 411-460 |
| Immunogen Region: | 411-460 aa |
| Specificity: | Phospho-Adducin Alpha (T445) Polyclonal Antibody detects endogenous levels of Adducin Alpha protein only when phosphorylated at T445. |
| Function | Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin. |
| Protein Name | Alpha-AdducinErythrocyte Adducin Subunit Alpha |
| Database Links | Reactome: R-HSA-264870Reactome: R-HSA-381038Reactome: R-HSA-5223345 |
| Cellular Localisation | CytoplasmCytoskeletonCell MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Alpha-Adducin antibodyAnti-Erythrocyte Adducin Subunit Alpha antibodyAnti-ADD1 antibodyAnti-ADDA antibody |
Information sourced from Uniprot.org
