| Host: |
Rabbit |
| Applications: |
WB/IHC/IF/ELISA |
| Reactivity: |
Human/Mouse/Rat/Monkey |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Phospho-ATP-citrate synthase-lyase-Ser455 (420-469 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ACLY |
| Gene ID: |
47 |
| Uniprot ID: |
ACLY_HUMAN |
| Immunogen Region: |
420-469 aa |
| Specificity: |
Phospho-ATP-citrate synthase (S455) Polyclonal Antibody detects endogenous levels of ATP-citrate synthase protein only when phosphorylated at S455. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human ATP-Citrate Lyase around the phosphorylation site of Ser454 at the amino acid range 420-469 |
| Function | Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis. |
| Protein Name | Atp-Citrate SynthaseAtp-CitratePro-S--LyaseAclCitrate Cleavage Enzyme |
| Database Links | Reactome: R-HSA-163765Reactome: R-HSA-6798695Reactome: R-HSA-75105 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Atp-Citrate Synthase antibodyAnti-Atp-Citrate antibodyAnti-Pro-S--Lyase antibodyAnti-Acl antibodyAnti-Citrate Cleavage Enzyme antibodyAnti-ACLY antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
