| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PGM1 |
| Gene ID: | 5236 |
| Uniprot ID: | PGM1_HUMAN |
| Immunogen Region: | 1-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PGM1 (NP_002624.2). |
| Immunogen Sequence: | MVKIVTVKTQAYQDQKPGTS GLRKRVKVFQSSANYAENFI QSIISTVEPAQRQEATLVVG GDGRFYMKEAIQLIARIAAA NGIGRLVIGQNGILSTPAVS CIIRKIKAIGGIILTASHNP GGPNGDFGIKFNISNGGPAP EAITDKIFQISKTIEEYAVC PDLKVDLGVLGKQQFDLENK FKPFTVEIVDSVEAYATMLR SIFDFSALKELLSGPNRLKI RIDAMHGVVGPYVKKILCE |
| Post Translational Modifications | Phosphorylation at Thr-467 by PAK1 significantly enhances enzymatic activity. |
| Function | Catalyzes the reversible isomerization of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate. The mechanism proceeds via the intermediate compound alpha-D-glucose 1,6-bisphosphate (Probable). This enzyme participates in both the breakdown and synthesis of glucose. |
| Protein Name | Phosphoglucomutase-1Pgm 1Glucose Phosphomutase 1 |
| Database Links | Reactome: R-HSA-3322077Reactome: R-HSA-5609974Reactome: R-HSA-6798695Reactome: R-HSA-70221Reactome: R-HSA-70370 |
| Cellular Localisation | Isoform 1: Cytoplasm |
| Alternative Antibody Names | Anti-Phosphoglucomutase-1 antibodyAnti-Pgm 1 antibodyAnti-Glucose Phosphomutase 1 antibodyAnti-PGM1 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and PGM1 knockout (KO) 293T cells, using [KO Validated] PGM1 Rabbit polyclonal antibody (STJ11100780) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89716/358198/STJ11100780_1__83532.1713122517.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and PGM1 knockout (KO) 293T cells, using [KO Validated] PGM1 Rabbit polyclonal antibody (STJ11100780) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
