Tissue Specificity | Mainly expressed in spermatogonia. Localized on the principle piece in the sperm (at protein level). Expression significantly decreased in the testis of elderly men. |
Function | Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. |
Protein Name | Phosphoglycerate Kinase 1Cell Migration-Inducing Gene 10 ProteinPrimer Recognition Protein 2Prp 2 |
Database Links | Reactome: R-HSA-70171Reactome: R-HSA-70263Reactome: R-HSA-9636667 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Phosphoglycerate Kinase 1 antibodyAnti-Cell Migration-Inducing Gene 10 Protein antibodyAnti-Primer Recognition Protein 2 antibodyAnti-Prp 2 antibodyAnti-PGK1 antibodyAnti-PGKA antibodyAnti-MIG10 antibodyAnti-OK antibodyAnti-SW-cl.110 antibody |
Information sourced from Uniprot.org