Host: | Alpaca |
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Alpaca monoclonal nanobody anti-Placenta Growth Factor is suitable for use in ELISA research applications. |
Clonality : | Monoclonal |
Clone ID : | SAA1244 |
Conjugation: | Unconjugated |
Isotype: | VHH-8His-Cys-tag |
Formulation: | 0.01M PBS, pH 7.4. |
Purification: | Purified by Nickel column. |
Concentration: | 1 mg/mL |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Gene Symbol: | PGF |
Gene ID: | 5228 |
Uniprot ID: | PLGF_HUMAN |
Post Translational Modifications | N-glycosylated. |
Function | Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. |
Protein Name | Placenta Growth FactorPlgf |
Database Links | Reactome: R-HSA-194313Reactome: R-HSA-195399 |
Cellular Localisation | SecretedThe Three Isoforms Are Secreted But Plgf-2 Appears To Remain Cell Attached Unless Released By Heparin |
Alternative Nanobody Names | Anti-Placenta Growth Factor nanobodyAnti-Plgf nanobodyAnti-PGF nanobodyAnti-PGFL nanobodyAnti-PLGF nanobody |
Information sourced from Uniprot.org