Anti-PGF/PlGF/PLGF nanobody [SAA1244] (STJN000232)

Anti-PGF/PlGF/PLGF nanobody [SAA1244] (STJN000232)

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STJN000232
£195.50 - £1,319.50
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Short Description :Alpaca monoclonal nanobody anti-Placenta Growth Factor is suitable for use in ELISA research applications.
Applications:ELISA
Host:Alpaca
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :SAA1244
Isotype:VHH-8His-Cys-tag
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:Purified by Nickel column.
Formulation:0.01M PBS, pH 7.4.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol:PGF
Gene ID:5228
Uniprot ID:PLGF_HUMAN
Post Translational Modifications N-glycosylated.
Function Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
Protein Name Placenta Growth Factor
Plgf
Database Links Reactome: R-HSA-194313
Reactome: R-HSA-195399
Cellular Localisation Secreted
The Three Isoforms Are Secreted But Plgf-2 Appears To Remain Cell Attached Unless Released By Heparin
Alternative Nanobody Names Anti-Placenta Growth Factor nanobody
Anti-Plgf nanobody
Anti-PGF nanobody
Anti-PGFL nanobody
Anti-PLGF nanobody

Information sourced from Uniprot.org

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