Anti-PGCD antibody (C-Term) {Biotin} (STJ502463)

Name: Anti-PGCD antibody (C-Term) {Biotin} (STJ502463)
SKU: STJ502463-100
Price: 686.55 USD
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationBiotin

IsotypeIgG

ImmunogenSynthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase D protein.

STJ502463-100

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Short Description	Rabbit polyclonal antibody anti-PGCD (C-Term) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry and Western Blot research applications.
Applications	CM/ELISA/ICC/IF/IHC/WB
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Biotin
Concentration	0.75-1.20 µg/µl
Purification	Affinity Purified
Dilution Range	WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:200 IHC: 1:200 ICC: 1:200 IF: 1:200 CFM: 1:200
Formulation	Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage Instruction	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol	Gucy2d
Gene ID	113911
Uniprot ID	GUC2D_RAT
Immunogen	Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase D protein.
Immunogen Region	C-Term

Tissue Specificity	Specifically expressed in a subpopulation of olfactory sensory neurons. Expressed in the cilia of the olfactory epithelium.
Function	Functions as an olfactory receptor activated by a urine odorant, uroguanylin. Activated as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2). Has guanylate cyclase activity upon binding of the ligand. Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency. Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference.
Protein Name	Guanylate Cyclase 2d Guanylate Cyclase - Olfactory One-Gc Olfactory Guanylyl Cyclase Gc-D Gc-D
Cellular Localisation	Cell Projection Cilium Membrane Single-Pass Type I Membrane Protein Colocalized With Ncald At The Apical Region Of The Cilia Coexpresses With Pde2
Alternative Antibody Names	Anti-Guanylate Cyclase 2d antibody Anti-Guanylate Cyclase - Olfactory antibody Anti-One-Gc antibody Anti-Olfactory Guanylyl Cyclase Gc-D antibody Anti-Gc-D antibody Anti-Gucy2d antibody Anti-Gucy2e antibody

Information sourced from Uniprot.org