| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Phosphoglycerate mutase 1 (14-64) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PGAM1 |
| Gene ID: |
5223 |
| Uniprot ID: |
PGAM1_HUMAN |
| Immunogen Region: |
14-64 |
| Specificity: |
This antibody detects endogenous levels of human PGAM1 |
| Immunogen: |
Synthesized peptide derived from human PGAM1 AA range: 14-64 |
| Post Translational Modifications | Acetylated at Lys-253, Lys-253 and Lys-254 under high glucose condition. Acetylation increases catalytic activity. Under glucose restriction SIRT1 levels dramatically increase and it deacetylates the enzyme. |
| Function | Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglyceratea crucial step in glycolysis, by using 2,3-bisphosphoglycerate. Also catalyzes the interconversion of (2R)-2,3-bisphosphoglycerate and (2R)-3-phospho-glyceroyl phosphate. |
| Protein Name | Phosphoglycerate Mutase 1Bpg-Dependent Pgam 1Phosphoglycerate Mutase Isozyme BPgam-B |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-70171Reactome: R-HSA-70263 |
| Alternative Antibody Names | Anti-Phosphoglycerate Mutase 1 antibodyAnti-Bpg-Dependent Pgam 1 antibodyAnti-Phosphoglycerate Mutase Isozyme B antibodyAnti-Pgam-B antibodyAnti-PGAM1 antibodyAnti-PGAMA antibodyAnti-CDABP0006 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
