| Short Description : | Rabbit polyclonal PFKFB2 (446-505) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PFKFB2 |
| Gene ID: | 5208 |
| Uniprot ID: | F262_HUMAN |
| Immunogen Region: | 446-505 |
| Immunogen Sequence: | RDKPTNNFPKNQTPVRMRRN SFTPLSSSNTIRRPRNYSVG SRPLKPLSPLRAQDMQEGAD |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 446-505 of human PFKFB2 (NP_006203.2). |
| Tissue Specificity | Heart. |
| Post Translational Modifications | Phosphorylation by AMPK stimulates activity. |
| Function | Synthesis and degradation of fructose 2,6-bisphosphate. |
| Protein Name | 6-Phosphofructo-2-Kinase/Fructose-2 -6-Bisphosphatase 26pf-2-K/Fru-2 -6-P2ase 2Pfk/Fbpase 26pf-2-K/Fru-2 -6-P2ase Heart-Type Isozyme Includes - 6-Phosphofructo-2-Kinase - Fructose-2 -6-Bisphosphatase |
| Database Links | Reactome: R-HSA-9634600 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-6-Phosphofructo-2-Kinase/Fructose-2 -6-Bisphosphatase 2 antibodyAnti-6pf-2-K/Fru-2 -6-P2ase 2 antibodyAnti-Pfk/Fbpase 2 antibodyAnti-6pf-2-K/Fru-2 -6-P2ase Heart-Type Isozyme Includes - 6-Phosphofructo-2-Kinase - Fructose-2 -6-Bisphosphatase antibodyAnti-PFKFB2 antibody |
Information sourced from Uniprot.org
