| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Peroxisomal targeting signal 2 receptor (204-253 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PEX7 |
| Gene ID: | 5191 |
| Uniprot ID: | PEX7_HUMAN |
| Immunogen Region: | 204-253 aa |
| Specificity: | Peroxin 7 Polyclonal Antibody detects endogenous levels of Peroxin 7 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human PEX7 at the amino acid range 204-253 |
| Function | Receptor required for the peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal. Specifically binds to cargo proteins containing a PTS2 peroxisomal targeting signal in the cytosol. Cargo protein-binding triggers interaction with PEX5 and formation of a ternary complex composed of PEX5 and PEX7 along with PTS2-containing cargo proteins, which is tranlocated into peroxisomes by passing through the PEX13-PEX14 docking complex. |
| Protein Name | Peroxisomal Targeting Signal 2 ReceptorPts2 ReceptorPeroxin-7 |
| Database Links | Reactome: R-HSA-9033241 |
| Cellular Localisation | CytoplasmCytosolPeroxisome MatrixTranslocated Into The Peroxisome Matrix Together With Pts2-Containing Cargo Proteins And Pex5 |
| Alternative Antibody Names | Anti-Peroxisomal Targeting Signal 2 Receptor antibodyAnti-Pts2 Receptor antibodyAnti-Peroxin-7 antibodyAnti-PEX7 antibodyAnti-PTS2R antibody |
Information sourced from Uniprot.org
