| Function | Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix. Plays a key role for peroxisome movement through a direct interaction with tubulin. |
| Protein Name | Peroxisomal Membrane Protein Pex14Pts1 Receptor-Docking ProteinPeroxin-14Peroxisomal Membrane Anchor Protein Pex14 |
| Database Links | Reactome: R-HSA-8866654Reactome: R-HSA-9033241Reactome: R-HSA-9603798 |
| Cellular Localisation | Peroxisome MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Peroxisomal Membrane Protein Pex14 antibodyAnti-Pts1 Receptor-Docking Protein antibodyAnti-Peroxin-14 antibodyAnti-Peroxisomal Membrane Anchor Protein Pex14 antibodyAnti-PEX14 antibody |
Information sourced from Uniprot.org
