Anti-Peroxiredoxin 5/PRDX5 antibody (53-214aa) [AT6A10] (STJA0041754)

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STJA0041754
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Host: Mouse
Applications: ELISA/WB/ICC/IF/FACS
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-Peroxiredoxin 5/PRDX5 (53-214aa) for use in ELISA, WB, ICC, IF and FACS in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : AT6A10
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol
Purification: By protein-A affinity chromatography
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: PRDX5
Gene ID: 25824
Uniprot ID: PRDX5_HUMAN
Immunogen Region: 53-214aa
Accession Number: NP_036226
Immunogen: Recombinant human Peroxiredoxin 5 (53-214aa) purified from E. coli
Tissue Specificity Widely expressed.
Post Translational Modifications S-palmitoylated. Palmitoylation occurs on the active site, inhibiting its reactivity.therefore PRDX5 palmitoylation status determines its antioxidant capacity. Isoform Mitochondrial: S-palmitoylated. Depalmitoylated by ABHD10.
Function Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
Protein Name Peroxiredoxin-5 - Mitochondrial
Alu Corepressor 1
Antioxidant Enzyme B166
Aoeb166
Liver Tissue 2d-Page Spot 71b
Plp
Peroxiredoxin V
Prx-V
Peroxisomal Antioxidant Enzyme
Tpx Type Vi
Thioredoxin Peroxidase Pmp20
Thioredoxin-Dependent Peroxiredoxin 5
Database Links Reactome: R-HSA-3299685
Reactome: R-HSA-5628897 P30044-2
Cellular Localisation Isoform Mitochondrial: Mitochondrion
Isoform Cytoplasmic+Peroxisomal: Cytoplasm
Peroxisome Matrix
Imported Into Peroxisomes Via Peroxisomal Targeting Signal 1 Receptor Pex5
Alternative Antibody Names Anti-Peroxiredoxin-5 - Mitochondrial antibody
Anti-Alu Corepressor 1 antibody
Anti-Antioxidant Enzyme B166 antibody
Anti-Aoeb166 antibody
Anti-Liver Tissue 2d-Page Spot 71b antibody
Anti-Plp antibody
Anti-Peroxiredoxin V antibody
Anti-Prx-V antibody
Anti-Peroxisomal Antioxidant Enzyme antibody
Anti-Tpx Type Vi antibody
Anti-Thioredoxin Peroxidase Pmp20 antibody
Anti-Thioredoxin-Dependent Peroxiredoxin 5 antibody
Anti-PRDX5 antibody
Anti-ACR1 antibody
Anti-SBBI10 antibody

Information sourced from Uniprot.org

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