| Host: |
Mouse |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Peroxiredoxin 1/PAG is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
SM5204 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% sodium azide, 100 Mu g/ml BSA and 50% glycerol. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB (H, M, R) 1:500-1:1000 |
| Storage Instruction: |
Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
| Gene Symbol: |
Prdx1 |
| Gene ID: |
18477 |
| Uniprot ID: |
PRDX1_MOUSE |
| Immunogen: |
KLH conjugated Synthetic peptide corresponding to Mouse Peroxiredoxin 1 |
| Post Translational Modifications | Phosphorylated on Thr-90 during the M-phase, which leads to a decrease in enzymatic activity. |
| Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation. |
| Protein Name | Peroxiredoxin-1Macrophage 23 Kda Stress ProteinOsteoblast-Specific Factor 3Osf-3Thioredoxin Peroxidase 2Thioredoxin-Dependent Peroxide Reductase 2Thioredoxin-Dependent Peroxiredoxin 1 |
| Database Links | Reactome: R-MMU-3299685Reactome: -MMU-5628897Reactome: -MMU-9818027 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Peroxiredoxin-1 antibodyAnti-Macrophage 23 Kda Stress Protein antibodyAnti-Osteoblast-Specific Factor 3 antibodyAnti-Osf-3 antibodyAnti-Thioredoxin Peroxidase 2 antibodyAnti-Thioredoxin-Dependent Peroxide Reductase 2 antibodyAnti-Thioredoxin-Dependent Peroxiredoxin 1 antibodyAnti-Prdx1 antibodyAnti-Msp23 antibodyAnti-Paga antibodyAnti-Tdpx2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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