| Post Translational Modifications | Phosphorylated on Thr-90 during the M-phase, which leads to a decrease in enzymatic activity. |
| Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation. |
| Protein Name | Peroxiredoxin-1Macrophage 23 Kda Stress ProteinOsteoblast-Specific Factor 3Osf-3Thioredoxin Peroxidase 2Thioredoxin-Dependent Peroxide Reductase 2Thioredoxin-Dependent Peroxiredoxin 1 |
| Database Links | Reactome: R-MMU-3299685Reactome: -MMU-5628897Reactome: -MMU-9818027 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Peroxiredoxin-1 antibodyAnti-Macrophage 23 Kda Stress Protein antibodyAnti-Osteoblast-Specific Factor 3 antibodyAnti-Osf-3 antibodyAnti-Thioredoxin Peroxidase 2 antibodyAnti-Thioredoxin-Dependent Peroxide Reductase 2 antibodyAnti-Thioredoxin-Dependent Peroxiredoxin 1 antibodyAnti-Prdx1 antibodyAnti-Msp23 antibodyAnti-Paga antibodyAnti-Tdpx2 antibody |
Information sourced from Uniprot.org
![Anti-Peroxiredoxin 1/PAG antibody [SM5204] (STJA0005204)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/180248/403746/STJA0005204_1__44245.1738950731.png?c=1 "Anti-Peroxiredoxin 1/PAG antibody [SM5204] (STJA0005204)")
![Anti-Peroxiredoxin 1/PAG antibody [SM5204] (STJA0005204)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/180248/403746/STJA0005204_1__44245.1738950731.png?c=1 "Anti-Peroxiredoxin 1/PAG antibody [SM5204] (STJA0005204)")
