Anti-Peripherin antibody (Full-Length) [7C5] (STJA0040754)

Name: Anti-Peripherin antibody (Full-Length) [7C5] (STJA0040754)
SKU: STJA0040754-100
Price: 528.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostMouse

ConjugationUnconjugated

IsotypeIgG

ImmunogenRecombinant full length rat Peripherin protein expressed in and purified from E.coli

STJA0040754-100

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Short Description	Mouse monoclonal anti-Peripherin (Full-Length) for use in ICC, IHC-F and WB in Cat, Human, Mouse, Other Mammals and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	ICC/IHC-F/WB
Host	Mouse
Reactivity	Cat/Human/Mouse/Other Mammals/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	7C5
Isotype	IgG
Conjugation	Unconjugated
Purification	Affinity-purified
Dilution Range	WB 0.5-2 µg/mL IHC 1-5 µg/mL ICC 1-5 µg/mL
Formulation	Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide
Storage Instruction	Spin vial briefly before opening. Reconstitute with 100 µL sterile-filtered, ultrapure water to achieve a 1 mg/mL concentration. Centrifuge to remove any insoluble material. Store lyophilized, unopened vial at 2-8°C or lower. After reconstitution, pr

Gene Symbol	PrphUniprot ID=PERI_RAT"
Immunogen	Recombinant full length rat Peripherin protein expressed in and purified from E.coli
Immunogen Region	Full-Length
Immunogen Sequence	Rat
Specificity	The specificity of this antibody has been confirmed by WB. This antibody detects ~57 kDa Peripherin protein. Human, mouse, feline. Predicted to react with other mammalian tissue.

Tissue Specificity	Expressed in hypoglossal motor neurons (at protein level). Expressed in the small and large sensory neurons of the dorsal root ganglion (at protein level). Expressed in cutaneous and muscular sensory neurons.
Post Translational Modifications	Phosphorylated.phosphorylation increases after nerve injury in regenerating neurons.
Function	Class-III neuronal intermediate filament protein. My form an independent structural network without the involvement of other neurofilaments or may cooperate with the neuronal intermediate filament proteins NEFL, NEFH, NEFM and INA to form a filamentous network. Assembly of the neuronal intermediate filaments may be regulated by RAB7A. Plays a role in the development of unmyelinated sensory neurons. May be involved in axon elongation and axon regeneration after injury. Inhibits neurite extension in type II spiral ganglion neurons in the cochlea.
Protein Name	Peripherin
Cellular Localisation	Cytoplasm Cytoskeleton Cell Projection Axon Perikaryon
Alternative Antibody Names	Anti-Peripherin antibody Anti-Prph antibody Anti-Prph1 antibody

Information sourced from Uniprot.org