Anti-Periostin antibody (1-100) [S2MR] (STJ11103642)

Name: Anti-Periostin antibody (1-100) [S2MR] (STJ11103642)
SKU: STJ11103642
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11103642

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Short Description	Rabbit monoclonal Periostin (1-100) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	S2MR
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	POSTN
Gene ID	10631
Uniprot ID	POSTN_HUMAN
Immunogen Region	1-100
Immunogen Sequence	MIPFLPMFSLLLLLIVNPIN ANNHYDKILAHSRIRGRDQG PNVCALQQILGTKKKYFSTC KNWYKKSICGQKTTVLYECC PGYMRMEGMKGCPAVLPIDH
Specificity	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Periostin (NP_001129406.1).

Tissue Specificity	Widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus, thyroid tissue and breast. Expressed in the kidney. Expressed in the lung. Up-regulated in epithelial ovarian tumors. Not expressed in normal ovaries. Also highly expressed at the tumor periphery of lung carcinoma tissue but not within the tumor. Overexpressed in breast cancers.
Post Translational Modifications	Gamma-carboxylation is controversial. Gamma-carboxyglutamated.gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation.this may be required for calcium binding. According to a more recent report, does not contain vitamin K-dependent gamma-carboxyglutamate residues.
Function	Induces cell attachment and spreading and plays a role in cell adhesion. Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX.
Protein Name	Periostin Pn Osteoblast-Specific Factor 2 Osf-2
Database Links
Cellular Localisation	Golgi Apparatus Secreted Extracellular Space Extracellular Matrix Colocalizes With Bmp1 In The Golgi
Alternative Antibody Names	Anti-Periostin antibody Anti-Pn antibody Anti-Osteoblast-Specific Factor 2 antibody Anti-Osf-2 antibody Anti-POSTN antibody Anti-OSF2 antibody

Information sourced from Uniprot.org