Anti-Perilipin antibody (Internal) (STJ71144)

SKU:
STJ71144-100
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal antibody anti-Perilipin (Internal) is suitable for use in ELISA and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:8000.
WB: Approx 60kDa band observed in Human Adipose lysates (calculated MW of 56.0kDa according to NP_002657.2). Recommended concentration: 1-3µg/ml. Primary incubation 1 hour at room temperatu
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: PLIN1
Gene ID: 5346
Uniprot ID: PLIN1_HUMAN
Immunogen Region: Internal
Accession Number: NP_002657.2
Immunogen Sequence: PREKPKRRVSDS
Post Translational Modifications Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet.
Function Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels.
Protein Name Perilipin-1
Lipid Droplet-Associated Protein
Database Links Reactome: R-HSA-163560
Reactome: R-HSA-381340
Reactome: R-HSA-9031528
Cellular Localisation Endoplasmic Reticulum
Lipid Droplet
Lipid Droplet Surface-Associated
Alternative Antibody Names Anti-Perilipin-1 antibody
Anti-Lipid Droplet-Associated Protein antibody
Anti-PLIN1 antibody
Anti-PERI antibody
Anti-PLIN antibody

Information sourced from Uniprot.org