| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Platelet endothelial aggregation receptor 1 (910-990 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PEAR1 |
| Gene ID: |
375033 |
| Uniprot ID: |
PEAR1_HUMAN |
| Immunogen Region: |
910-990 aa |
| Specificity: |
PEAR1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 910-990 |
| Post Translational Modifications | Phosphorylated in the intracellular domain on tyrosine residues. Phosphorylated on tyrosine residues by SRC. Tyrosine phosphorylation is detected upon platelet aggregation stimulated by collagen, TRAP and thrombin and platelet-platelet contacts but not after platelet activation. Tyrosine phosphorylation enhanced its association with SHC1 and SHC2. |
| Function | When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells. |
| Protein Name | Platelet Endothelial Aggregation Receptor 1Hpear1Multiple Epidermal Growth Factor-Like Domains Protein 12Multiple Egf-Like Domains Protein 12 |
| Cellular Localisation | Cell MembraneSingle-Pass Membrane ProteinDetected On The Cell Surface In Resting Platelets |
| Alternative Antibody Names | Anti-Platelet Endothelial Aggregation Receptor 1 antibodyAnti-Hpear1 antibodyAnti-Multiple Epidermal Growth Factor-Like Domains Protein 12 antibodyAnti-Multiple Egf-Like Domains Protein 12 antibodyAnti-PEAR1 antibodyAnti-MEGF12 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
