• Immunofluorescence analysis of C6 cells using PDP2 Rabbit polyclonal antibody (STJ119385) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Western blot analysis of various lysates using PDP2 Rabbit polyclonal antibody (STJ119385) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-PDP2 antibody (67-250) (STJ119385)

SKU:
STJ119385

£112.50 - £524.50
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PDP2
Gene ID: 57546
Uniprot ID: PDP2_HUMAN
Immunogen Region: 67-250
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 67-250 of human PDP2 (NP_065837.1).
Immunogen Sequence: STEEDDFHLQLSPEQINEVL RAGETTHKILDLESRVPNSV LRFESNQLAANSPVEDRRGV ASCLQTNGLMFGIFDGHGGH ACAQAVSERLFYYVAVSLMS HQTLEHMEGAMESMKPLLPI LHWLKHPGDSIYKDVTSVHL DHLRVYWQELLDLHMEMGLS IEEALMYSFQRLDSDISLEI QAPL
Function Mitochondrial enzyme that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex (PDC), thereby stimulating the conversion of pyruvate into acetyl-CoA. Acts as a crucial regulator of T cell metabolism and function, with a particular focus on T-helper Th17.
Protein Name Pyruvate Dehydrogenase Acetyl-Transferring-Phosphatase 2 - Mitochondrial
Pdp 2
Pyruvate Dehydrogenase Phosphatase Catalytic Subunit 2
Pdpc 2
Database Links Reactome: R-HSA-204174
Cellular Localisation Mitochondrion
Alternative Antibody Names Anti-Pyruvate Dehydrogenase Acetyl-Transferring-Phosphatase 2 - Mitochondrial antibody
Anti-Pdp 2 antibody
Anti-Pyruvate Dehydrogenase Phosphatase Catalytic Subunit 2 antibody
Anti-Pdpc 2 antibody
Anti-PDP2 antibody
Anti-KIAA1348 antibody

Information sourced from Uniprot.org

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