| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PDIA2 |
| Gene ID: | 64714 |
| Uniprot ID: | PDIA2_HUMAN |
| Immunogen Region: | 326-525 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 326-525 of human PDIA2 (NP_006840.2). |
| Immunogen Sequence: | FGLKAEAAPTLRLVNLETTK KYAPVDGGPVTAASITAFCH AVLNGQVKPYLLSQEIPPDW DQRPVKTLVGKNFEQVAFDE TKNVFVKFYAPWCTHCKEMA PAWEALAEKYQDHEDIIIAE LDATANELDAFAVHGFPTLK YFPAGPGRKVIEYKSTRDLE TFSKFLDNGGVLPTEEPPEE PAAPFPEPPANSTMGSKEEL |
| Tissue Specificity | Highly expressed in pancreas (at protein level). |
| Post Translational Modifications | The disulfide-linked homodimer exhibits an enhanced chaperone activity. Glycosylated. |
| Function | Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins. |
| Protein Name | Protein Disulfide-Isomerase A2 Pancreas-Specific Protein Disulfide Isomerase Pdip |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Antibody Names | Anti-Protein Disulfide-Isomerase A2 antibody Anti-Pancreas-Specific Protein Disulfide Isomerase antibody Anti-Pdip antibody Anti-PDIA2 antibody Anti-PDIP antibody |
Information sourced from Uniprot.org