Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-PDIA2 (326-525) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PDIA2 |
Gene ID: |
64714 |
Uniprot ID: |
PDIA2_HUMAN |
Immunogen Region: |
326-525 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 326-525 of human PDIA2 (NP_006840.2). |
Immunogen Sequence: |
FGLKAEAAPTLRLVNLETTK KYAPVDGGPVTAASITAFCH AVLNGQVKPYLLSQEIPPDW DQRPVKTLVGKNFEQVAFDE TKNVFVKFYAPWCTHCKEMA PAWEALAEKYQDHEDIIIAE LDATANELDAFAVHGFPTLK YFPAGPGRKVIEYKSTRDLE TFSKFLDNGGVLPTEEPPEE PAAPFPEPPANSTMGSKEEL |
Tissue Specificity | Highly expressed in pancreas (at protein level). |
Post Translational Modifications | The disulfide-linked homodimer exhibits an enhanced chaperone activity. Glycosylated. |
Function | Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins. |
Protein Name | Protein Disulfide-Isomerase A2Pancreas-Specific Protein Disulfide IsomerasePdip |
Cellular Localisation | Endoplasmic Reticulum Lumen |
Alternative Antibody Names | Anti-Protein Disulfide-Isomerase A2 antibodyAnti-Pancreas-Specific Protein Disulfide Isomerase antibodyAnti-Pdip antibodyAnti-PDIA2 antibodyAnti-PDIP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance