| Host: |
Rabbit |
| Applications: |
IHC |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PDGFA (21-110) is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PDGFA |
| Gene ID: |
5154 |
| Uniprot ID: |
PDGFA_HUMAN |
| Immunogen Region: |
21-110 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 21-110 of human PDGFA (NP_002598.4). |
| Immunogen Sequence: |
EEAEIPREVIERLARSQIHS IRDLQRLLEIDSVGSEDSLD TSLRAHGVHATKHVPEKRPL PIRRKRSIEEAVPAVCKTRT VIYEIPRSQV |
| Function | Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB. |
| Protein Name | Platelet-Derived Growth Factor Subunit APdgf Subunit APdgf-1Platelet-Derived Growth Factor A ChainPlatelet-Derived Growth Factor Alpha Polypeptide |
| Database Links | Reactome: R-HSA-114608 P04085-1Reactome: R-HSA-1257604Reactome: R-HSA-186763Reactome: R-HSA-186797Reactome: R-HSA-2219530Reactome: R-HSA-3000171Reactome: R-HSA-5673001Reactome: R-HSA-6811558 |
| Cellular Localisation | SecretedReleased By Platelets Upon Wounding |
| Alternative Antibody Names | Anti-Platelet-Derived Growth Factor Subunit A antibodyAnti-Pdgf Subunit A antibodyAnti-Pdgf-1 antibodyAnti-Platelet-Derived Growth Factor A Chain antibodyAnti-Platelet-Derived Growth Factor Alpha Polypeptide antibodyAnti-PDGFA antibodyAnti-PDGF1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
