| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Retinal rod rhodopsin-sensitive cGMP 3 NA, 5 cyclic phosphodiesterase subunit delta (89-139 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PDE6D |
| Gene ID: |
5147 |
| Uniprot ID: |
PDE6D_HUMAN |
| Immunogen Region: |
89-139 aa |
| Specificity: |
This antibody detects endogenous levels of PDE6D at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human PDE6D at the amino acid range 89-139 |
| Function | Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate. |
| Protein Name | Retinal Rod Rhodopsin-Sensitive Cgmp 3' -5'-Cyclic Phosphodiesterase Subunit DeltaGmp-Pde DeltaProtein P17 |
| Database Links | Reactome: R-HSA-5624958Reactome: R-HSA-9648002 |
| Cellular Localisation | CytoplasmCytosolCytoplasmic Vesicle MembranePeripheral Membrane ProteinCytoskeletonCilium Basal Body |
| Alternative Antibody Names | Anti-Retinal Rod Rhodopsin-Sensitive Cgmp 3' -5'-Cyclic Phosphodiesterase Subunit Delta antibodyAnti-Gmp-Pde Delta antibodyAnti-Protein P17 antibodyAnti-PDE6D antibodyAnti-PDED antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
