Anti-PDE6D antibody (1-150) (STJ116962)

SKU:
STJ116962
£112.50 - £524.50
Free Shipping
Processing The item has been added

Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IF/ICC:1:50-1:100
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PDE6D
Gene ID: 5147
Uniprot ID: PDE6D_HUMAN
Immunogen Region: 1-150
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human PDE6D (NP_002592.1).
Immunogen Sequence: MSAKDERAREILRGFKLNWM NLRDAETGKILWQGTEDLSV PGVEHEARVPKKILKCKAVS RELNFSSTEQMEKFRLEQKV YFKGQCLEEWFFEFGFVIPN STNTWQSLIEAAPESQMMPA SVLTGNVIIETKFFDDDLLV STSRVRLFYV
Tissue Specificity Widely expressed. Detected in various tissues including spleen, prostate gland, testis, ovary, small intestine, colon, retina, and peripheral blood.
Function Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
Protein Name Retinal Rod Rhodopsin-Sensitive Cgmp 3' -5'-Cyclic Phosphodiesterase Subunit Delta
Gmp-Pde Delta
Protein P17
Database Links Reactome: R-HSA-5624958
Reactome: R-HSA-9648002
Cellular Localisation Cytoplasm
Cytosol
Cytoplasmic Vesicle Membrane
Peripheral Membrane Protein
Cytoskeleton
Cilium Basal Body
Alternative Antibody Names Anti-Retinal Rod Rhodopsin-Sensitive Cgmp 3' -5'-Cyclic Phosphodiesterase Subunit Delta antibody
Anti-Gmp-Pde Delta antibody
Anti-Protein P17 antibody
Anti-PDE6D antibody
Anti-PDED antibody

Information sourced from Uniprot.org