• Immunofluorescence analysis of U-2 OS cells using PDE6D Rabbit polyclonal antibody (STJ116962) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of L929 cells using PDE6D Rabbit polyclonal antibody (STJ116962) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Western blot analysis of various lysates using PDE6D Rabbit polyclonal antibody (STJ116962) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-PDE6D antibody (1-150) (STJ116962)

SKU:
STJ116962

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PDE6D (1-150) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:100
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PDE6D
Gene ID: 5147
Uniprot ID: PDE6D_HUMAN
Immunogen Region: 1-150
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human PDE6D (NP_002592.1).
Immunogen Sequence: MSAKDERAREILRGFKLNWM NLRDAETGKILWQGTEDLSV PGVEHEARVPKKILKCKAVS RELNFSSTEQMEKFRLEQKV YFKGQCLEEWFFEFGFVIPN STNTWQSLIEAAPESQMMPA SVLTGNVIIETKFFDDDLLV STSRVRLFYV
Tissue Specificity Widely expressed. Detected in various tissues including spleen, prostate gland, testis, ovary, small intestine, colon, retina, and peripheral blood.
Function Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
Protein Name Retinal Rod Rhodopsin-Sensitive Cgmp 3' -5'-Cyclic Phosphodiesterase Subunit Delta
Gmp-Pde Delta
Protein P17
Database Links Reactome: R-HSA-5624958
Reactome: R-HSA-9648002
Cellular Localisation Cytoplasm
Cytosol
Cytoplasmic Vesicle Membrane
Peripheral Membrane Protein
Cytoskeleton
Cilium Basal Body
Alternative Antibody Names Anti-Retinal Rod Rhodopsin-Sensitive Cgmp 3' -5'-Cyclic Phosphodiesterase Subunit Delta antibody
Anti-Gmp-Pde Delta antibody
Anti-Protein P17 antibody
Anti-PDE6D antibody
Anti-PDED antibody

Information sourced from Uniprot.org

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